PhD position on Compilation Techniques for Flow-based Microfluidic Biochips

DTU compute would like to invite applications for a 3-year PhD position starting March 1st, 2015 (or later). The project is financed by IDEA4CPS.

The Embedded Systems Engineering section (http://www.compute.dtu.dk/english/research/ESE) at DTU Compute is looking a PhD student in the area of biochemical application compilation techniques for flow-based microfluidic biochips.

Description

Microfluidic biochips (also known as lab-on-a-chip devices) are an alternative to conventional biochemical laboratories, and are revolutionizing biology. We are interested in a type of biochips where the basic building block is a micro-valve. By combining these micro-valves, more complex units (see the videos on this page (http://groups.csail.mit.edu/cag/biostream/)) such as mixers, switches, multiplexers can be built; hence, the technology is called microfluidic Very Large Scale Integration (mVLSI). These biochips are becoming increasingly complex, with thousands of components, but are designed, fabricated and programmed manually, which is extremely labor intensive and error prone.

Our group has been working on the modeling and optimization of flow-based biochips, see these slides (https://dl.dropboxusercontent.com/u/14537141/minhass_slides_thesis2.pptx) and this PhD thesis (https://dl.dropboxusercontent.com/u/14537141/biochips BSc/wajid_phdthesis.pdf) for a summary of our research. Recently, two high-level biochemical protocol languages have been proposed: Aqua and BioCoder. In this PhD project, we are interested in developing compilation techniques for biochemical applications written in Aqua or BioCoder, with a focus on automatic fluid management. Compared to computers, the use of a “fluid” variable depletes it; the low volumes are susceptible to evaporation and imperfect operations, resulting in volume variability. Fluid management cannot be exposed to the end-user: even simple calculations, such as the required flow rates, can be challenging. The automatic fluid management has to ensure that there is no overflow and underflow of liquids, keep track of dead volumes until they are disposed to waste. The fluids are often hard to obtain samples and expensive reagents, and they have to be judiciously used.

Nr of positions available : 1

Research Fields

Computer science - Other

Career Stage

Early stage researcher or 0-4 yrs (Post graduate) 

Research Profiles

First Stage Researcher (R1) 

Comment/web site for additional job details

Application
To apply, please read the full job advertisement at www.career.dtu.dk 


Application deadline: 1 March 2015
DTU Compute conducts research and provides teaching in the fields of mathematics, modeling and computer science. The expanding mass of information and the increasingly complex use of advanced technology in society demand development of advanced computer based mathematical models and calculations. The unique skills of the department are in high demand in IT innovation and production.

DTU is a technical university providing internationally leading research, education, innovation and public service. Our staff of 5,700 advance science and technology to create innovative solutions that meet the demands of society; and our 10,000 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government, and public agencies

Application website

http://www.career.dtu.dk

Application Deadline

01/03/2015

Envisaged Job Starting Date

01/03/2015