Genetic Epidemiologist or Computational Biologist

Dr. Gibbons is committed to mentor/develop a critical mass of talented investigators who will emerge with independent research programs and cross-disciplinary collaborative research teams elucidating racial and ethnic disparities in cardiovascular health.

Description

A postdoctoral training position is currently available in Dr. Gary H. Gibbons’ research program in the Genomics of Metabolic, Cardiovascular and Inflammatory Disease Branch of the National Human Genome Research Institute (NHGRI). The successful candidate will join Dr. Gibbons’ multi-disciplinary research team composed of research fellows, staff and students with a range of expertise including: genetics, epidemiology, health disparities research, bioinformatics, systems biology, clinical science, computational biology and molecular medicine. The successful candidate will join an intellectually vibrant, interactive and collaborative community of investigators within our Branch led by Dr. Charles Rotimi in the NHGRI.

Dr. Gibbons’ research program is particularly interested in elucidating the systems biology, bio-social interactions and molecular networks that mediate the predisposition of individuals of African ancestry to cardio-metabolic disorders and cardiovascular complications (hypertension, obesity, cardiovascular disease, stroke). The conceptual framework of the program seeks to integrate a multi-level approach that incorporates both systems biology and a socio-ecologic model in understanding the multi-dimensional determinants of ancestry-related differences in health and disease. Several of the ongoing projects in Dr. Gibbons’ group include: 1) defining ancestry-related genetic variants associated with severe hypertension in African-Americans; 2) characterizing the bio-social determinants of the epigenome and transcriptome in African-Americans at risk for cardiovascular disease; and 3) defining the influence of psychosocial and environmental factors on the epigenome and transcriptome in African-Americans in health and disease. Our lab uses state-of-the-art  high-throughput ‘Omic’ technologies in conjunction with our well phenotyped datasets of African-Americans to identify, categorize and evaluate genomic-phenomic relationships that contribute to race-ancestry differences in the prevalence, severity, and treatment responsiveness of minority population’s at-risk for cardiovascular disease..   

The qualified candidates should be highly motivated and have a doctoral degree with research experience and training in the fields of: genetics, genetic epidemiology, statistical genetics, computational biology, systems biology, bioinformatics, molecular biology or related fields upon the start date in the lab. Previous post-doctoral research experience in these fields is desirable. The ideal candidate should have experience in analyzing high-throughput genomic data, next-generation sequencing pipelines, genotype-phenotype associations, and the application of state-of-the-art statistical methods. Prior experience using bioinformatics tools and/or computer programming skills is highly desirable. Applicants must possess good communi...

Nr of positions available : 1

Research Fields

Biological sciences 
Biological sciences 
Biological sciences 
Biological sciences 
Biological sciences 
Biological sciences 
Biological sciences 
Physics 
Computer science 
Medical sciences 
Medical sciences 
Medical sciences

Career Stage

Early stage researcher or 0-4 yrs (Post graduate) 
Experienced researcher or 4-10 yrs (Post-Doc) 
More Experienced researcher or >10 yrs (Senior) 

Research Profiles

Not defined

Comment/web site for additional job details

NIH is located in Bethesda Maryland

Application website

http://jobs.sciencecareers.org/apply/346517/genetic-epidemiologist-or-computational-biologist-/?TrackID=84598

Application Deadline

24/12/2014

Envisaged Job Starting Date

29/10/2014near Washington DC